M3142

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M3142

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Meperidine hydrochloride

Synonym:Pethidine hydrochloride, 1-Methyl-4-phenylpiperidine-4-carboxylic acid ethyl ester hydrochloride
CAS Number:50-13-5
Linear Formula:C15H21NO2 · HCl
Molecular Weight:283.79
EC Number:200-013-3
MDL number:MFCD00058210
PubChem Substance ID:24896799

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Description

Biochem/physiol ActionsPhenylpiperidine analgesic; sedative; μ opioid receptor agonist with greater κ opioid receptor agonist activity than morphine.

Properties

drug controlUSDEA Schedule II; Home Office Schedule 2; stupéfiant; kontrollierte Droge in Deutschland; regulated under CDSA - not available from Sigma-Aldrich Canada

Safety

Personal Protective EquipmentEyeshields, Faceshields, Gloves, type P2 (EN 143) respirator cartridges
Hazard CodesT
Risk Statements25
Safety Statements26-36/37/39-45
RIDADRUN2811 6.1/PG 3
WGK Germany3
RTECSNS5950000

References

referenceAlt, A., et al., Stimulation of guanosine-5'-O-(3-[35S]thio)triphosphate binding by endogenous opioids acting at a cloned mu receptor. J. Pharmacol. Exp. Ther. 286, 282-288, (1998) Abstract
 Emmerson, P.J., et al., Characterization of opioid agonist efficacy in a C6 glioma cell line expressing the mu opioid receptor. J. Pharmacol. Exp. Ther. 278, 1121-1127, (1996) Abstract
 Yoburn, B.C., et al., Supersensitivity to opioid analgesics following chronic opioid antagonist treatment: relationship to receptor selectivity. Pharmacol. Biochem. Behav. 51, 535-539, (1995) Abstract
 Abram, S.E., et al., Assessment of the potency and intrinsic activity of systemic versus intrathecal opioids in rats. Anesthesiology 87, 127-134, (1997) Abstract